Diagnostic Test Kit for Quantitative estimation of Total and Direct Bilirubin in Human Serum/Plasma.
CLINICAL SIGNIFICANCE: Hyperbilirubinaemia is a characteristic of Jaundice. In Hemolytic Jaundice and Neo-natal Jaundice, usually Unconjugated Bilirubin level increases without corresponding increase in Conjugated Bilirubin.
In Viral Hepatitis, Toxic Hepatitis and Cirrhosis, there is a overall damage to Liver cells. Hence,the ability of Liver to form Conjugated Bilirubin decreases, resulting in Un-conjugated Bilirubin in Serum.
In obstructive Jaundice there is an increase in both Unconjugated and Conjugated Bilirubin.